Publikation: Methode zur Quantifizierung von 8-Methoxypsoralen mittels LC-MS/MS für die Offline-ECP

2016-12-15 09:12

Extracorporeal photopheresis (ECP) is an efficient method to treat various autoimmune diseases, cutaneous T-cell lymphoma, and graft-versus-host disease. It is based on the ex vivo inactivation of lymphocytes by 8-methoxypsoralen (8-MOP)/UV light treatment. Despite the adhesive, lipophilic nature of 8-MOP, no quality control is established for the ECP procedure.

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